PDRN (Salmon Sperm) Therapy
Polydeoxyribonucleotide (PDRN) Salmon DNA skin therapy that supports repair for smoother, fresher looking skin.
What Is PDRN (Salmon DNA) Therapy?
PDRN (polydeoxyribonucleotide) therapy is an advanced regenerative procedure that uses highly purified DNA fragments derived from salmon to stimulate your body’s natural ability to heal and regenerate tissue. You may be drawn to this treatment due to chronic skin concerns such as fine lines, acne scars, hyperpigmentation, or decreased elasticity—often resulting from aging, environmental exposure, inflammation, or slowed cellular repair.
These changes in your skin can develop gradually, but still significantly impact your confidence and overall well-being. You might notice a rough or uneven texture, lingering discoloration, or acne scarring that remains resistant to conventional skincare products and treatments. These visible concerns are often rooted in impaired cellular repair, reduced microcirculation, and decreased collagen production—and may be accompanied by many other symptoms.
At Michael Rothman MD, we approach these concerns using a holistic, functional and metabolic medicine framework. By enhancing cellular communication and optimizing your body’s ability to regenerate and repair damaged tissue, PDRN therapy offers a non-toxic, scientifically validated option for true skin rejuvenation. Rather than masking symptoms, this treatment initiates deep structural changes—leaving your skin visibly stronger, healthier, and more resilient.
What Conditions Does PDRN Treat?
Rejuran PDRN Serum are primarily sought by individuals experiencing premature aging, chronic skin damage, or poor wound healing. While every patient presents differently, some of the most common concerns include:
- Fine Lines and Wrinkles: Subtle or deep lines caused by repetitive movement, aging, or dehydration
- Loss of Skin Elasticity: A sagging or “loose” appearance, especially around your jawline, cheeks, and neck
- Dull or Uneven Skin Tone: A lackluster complexion often caused by impaired skin turnover
- Age Spots and Sun Damage: Hyperpigmented areas resulting from UV exposure and accumulated DNA damage
- Acne Scars: Pitted or discolored skin resulting from long-standing inflammation or poorly healed acne
- Dry, Dehydrated Skin: Flakiness or tightness even with moisturizers, due to impaired moisture retention
- Delayed Wound Healing: Persistent scabbing or slow recovery from skin injuries or procedures
- Inflammatory Skin Conditions: Redness, sensitivity, or chronic irritation
- Skin Thinning: A translucent or fragile appearance that reveals underlying vessels or bruises easily
- Textural Irregularities: Enlarged pores, roughness, or uneven skin surfaces
If you’re experiencing any of these symptoms—and especially if you’ve struggled to find effective results from conventional treatments—PDRN therapy may offer a solution. Our functional and metabolic medicine approach can help restore your skin’s integrity and revitalize your skin’s function from the cellular level outward.
Rejuran, a specific brand of PDRN products, has become one of the most recognized names in regenerative aesthetics due to Rejuran’s high purity and clinically demonstrated outcomes. The effectiveness of this PDRN skin booster stems from dual mechanisms: promoting angiogenesis (new blood vessel formation) and stimulating collagen production, while simultaneously supporting DNA repair pathways essential to youthful, resilient skin.
Ready to Experience True Regeneration?
If you’re ready to go beyond surface-level fixes and restore your skin from the inside out, schedule your personalized PDRN therapy consultation today. Call us at 732-268-7663 or book online now
How PDRN Transforms Your Skin at the Cellular Level
Our advanced PDRN skin booster treatment represents a breakthrough in regenerative medicine, harnessing your body’s natural healing power to achieve results that traditional methods simply can’t match. Rather than masking symptoms or forcing unnatural processes, this innovative technology activates the cellular mechanisms you were born with, optimizing them for superior healing outcomes. The science behind this approach targets multiple healing pathways simultaneously, creating a comprehensive solution that addresses everything from blood flow to cellular regeneration. Here’s how this cutting-edge technology transforms your body’s healing process:
- Activates Natural Healing – Works with your body’s own repair mechanisms to dramatically speed recovery
- Boosts Blood Flow – Increases circulation to deliver essential nutrients and oxygen to treated areas
- Stimulates Collagen Production – Encourages your skin to produce more of the protein that keeps it firm and youthful
- Reduces Inflammation – Naturally minimizes swelling, discomfort, and scarring during healing
- Proven Clinical Results – Studies confirm faster, better healing even for challenging wounds like diabetic ulcers
- Energizes Skin Cells – Helps your cells work more efficiently at the cellular level
- Repairs Sun Damage – Addresses damage from UV exposure for healthier skin
- Rejuvenates Aging Cells – Helps older cells function like younger ones again
The Result: Faster healing, healthier-looking skin, and less visible scarring through your body’s own natural processes.
Why PDRN Stands Above the Rest
While many treatments promise skin rejuvenation, few deliver the comprehensive cellular transformation that PDRN therapy provides. Unlike temporary fixes or harsh interventions, PDRN works harmoniously with your body’s natural healing wisdom to create lasting, meaningful change. Here’s how our preferred regenerative approach compares to other popular treatments:
| Treatment Type | Benefits | Limitations |
|---|---|---|
|
PRP |
Natural, uses patient’s own blood |
Has variable outcomes |
|
Hyaluronic Acid Fillers |
Immediate volume restoration |
No regenerative effects |
|
Laser Resurfacing |
Improves texture and tone |
Requires longer downtime |
|
PDRN Therapy (Rejuran) |
Regenerative, hydrating, collagen stimulating |
Requires multiple sessions for best results |
How Is PDRN Therapy Delivered?
PDRN is administered through microneedling—a minimally invasive technique that creates microscopic channels in your skin to allow the serum to penetrate deeply. This method enhances absorption and activates your skin’s healing response. While the treatment is generally well tolerated, it’s important to know that microneedling involves the use of very fine needles. If you are uncomfortable with needles or concerned about downtime, we encourage you to reach out with questions so we can walk you through the process and expectations.
See the Remarkable Results for Yourself
These real patient photos show the dramatic healing improvements achieved with our advanced treatment technology. Each case demonstrates how activating your body’s natural repair mechanisms leads to superior outcomes that speak for themselves. Individual results may vary.
Your Path to Radiant Transformation Awaits
1
Single Treatment (Microneedling with PDRN, Introductory Pricing)
$250 per section
2
Series Package
$800 for 4 sessions (nonrefundable)
3
Treatment Schedule
4 sessions, spaced 4–6 weeks apart
4
Maintenance
As needed, every 4–6 months
Meet Delma Benvenuti-Rothman your PDRN Aesthetician
Delma Benvenuti-Rothman is a Master Medical Aesthetician and Co-owner with over 19 years of specialized expertise in advanced PDRN skincare and aesthetic medicine. Drawing from her unique heritage as the granddaughter of a Brazilian native Indian, she integrates ancestral beauty wisdom with cutting-edge medical-grade treatments to deliver exceptional results for her patients.
Originally from Rio de Janeiro, Delma’s career began in Brazil’s fashion industry before establishing herself in New York’s prestigious modeling scene. Her extensive background in fashion and beauty standards provides invaluable insight into aesthetic excellence that continues to inform her practice today.
Licensed as a Medical Aesthetician since 2007, Delma has pursued comprehensive postgraduate education in specialized treatments including medical-grade chemical peels and manual lymphatic drainage with Vodder-Schöll of Austria. Her functional and metabolic approach considers each patient’s unique skin biology, lifestyle factors, and aesthetic goals to develop personalized treatment protocols that honor both traditional healing practices and modern medical aesthetics. Patients can expect meticulous care and transformative results through her seamless blend of art, science, and cultural wisdom.
Frequently Asked Questions
Most patients begin to notice improved hydration, elasticity, and brightness after the second session, with more dramatic improvements in skin structure and scarring after 3–4 treatments. The regenerative effects continue to build for months as PDRN stimulates your body’s natural collagen synthesis and cellular repair mechanisms. Peak results typically appear 12-16 weeks after completing your treatment series, with individual outcomes varying based on skin condition, age, and lifestyle factors.
PDRN therapy is a minimal-downtime treatment with mild redness or pinpoint swelling that typically resolves within 24–48 hours. You can resume regular skincare and light makeup the next day, avoiding active ingredients like retinoids for the first 24 hours. Workouts can be resumed after 48 hours, and we recommend using SPF 30+ and avoiding excessive sun exposure during the first week.
For optimal results, we recommend a series of 4 sessions spaced 4–6 weeks apart, followed by maintenance treatments as needed. This protocol is based on clinical research showing peak efficacy with this treatment interval, allowing for complete cellular regeneration cycles. Some patients with severe skin damage may benefit from additional sessions, which we’ll discuss during your personalized consultation.
PDRN has an exceptional safety profile backed by Phase III clinical trials, with side effects being minimal and temporary. The most common effects include mild redness, pinpoint swelling, and temporary sensitivity at injection sites, all of which typically resolve within 24-48 hours. Comprehensive safety studies show no toxic effects on vital organs, confirming PDRN is biocompatible and well-tolerated by human skin.
Yes, PDRN integrates beautifully with other regenerative treatments like PRP, microneedling, laser therapy, and medical-grade chemical peels for enhanced synergistic benefits. Our functional medicine approach creates personalized protocols that optimize timing and combination of treatments based on your specific concerns. Some combinations may be performed simultaneously, while others work best when appropriately spaced for maximum effectiveness
Results can last 6–12 months depending on your lifestyle, skin condition, age, and environmental factors like sun exposure and overall health. Maintenance every 4–6 months is recommended for sustained regenerative benefits and continued collagen stimulation. Our functional medicine approach includes ongoing assessment to adjust maintenance schedules, ensuring you maintain optimal results while supporting your body’s natural regenerative capacity.
Ready to Experience True Regeneration?
If you’re ready to go beyond surface-level fixes and restore your skin from the inside out, schedule your personalized PDRN therapy consultation today. Call us at 732-268-7663 or book online now
