The Work of Emanuel Revici MD
- Born in Romania in 1896, deceased in 1997
- A brilliant scientist and medical doctor
- Spent decades doing research in physiopathology
- Published his seminal book in 1961 describing a previously unknown homeostatic control mechanism
- Revici’s license to practice medicine was revoked in 1993
- Revici’s contributions have been marginalized in conventional medicine despite profound implications of his work
Anabolic – Catabolic Imbalances
- A common, but rarely recognized cause of chronic illness
- Also referred to as Anaerobic/Dysaerobic imbalance
- The Anaerobic imbalance is also known as the “Warburg Effect”- or anerobic glycolysis – also associated with “reductive stress”
- The Dysaerobic imbalance is associated with “oxidative stress”
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Balance Between Anabolic and Catabolic Tendencies is Vital for Health
- In a balanced state there are sufficient sterols and fatty acids to allow the cells to produce energy in an efficient manner
- Enough sterols to control oxidative stress
- Enough fatty acids to facilitate oxidative metabolism
- Appropriate membrane permeability
- Appropriate pH balance between intracellular and extracellular compartments
Anabolic/Catabolic Balance is Achieved Toward the Middle of the Curve
A Balance Between Fatty Acids and Sterols
Anabolic (Anaerobic)
- Caused by excessive sterol activity within lipid bilayer of cell and mitochondrial membranes
- The relative lack of free fatty acids available to bond with oxygen leads to an anaerobic metabolic state
- This anaerobic state leads to increased growth of connective tissue and dedifferentiated growth
- Decreased membrane permeability
- Excess tissue acidity and excess systemic alkalinity
Too Many Sterols
Anaerobic Patterns
- Common Symptoms -constipation, sleepy fatigue, polyuria, depression, burning pain (tissue acidity), adverse response to prednisone
- Lab Findings – may have -low CRP, low serum cholesterol, high estrogen, high progesterone, high cortisol, increased symptoms during mid-luteal phase of cycle
- Metabolic Tests – low urine SG < 15, high urine pH > 6.2, low saliva pH < 6.7, slow absorption of skin wheel
- Benefit from relatively low cholesterol foods
- Benefit from sulfur products
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Anaerobic Overview
- Anaerobic (lack of oxygen- also known as anaerobic glycoysis = Warburg Effect) – Lactic acid is a product of anaerobic metabolism
- Treatment – Relatively low cholesterol diet, Oxytonic (sodium thiosulfate), Oxygenic A ,Taurine.
Catabolic (Dysaerobic)
- Caused by excessive fatty acid activity within lipid bilayer of cell and mitochondrial membranes
- The relative lack of sterols available to bind to fatty acids exposes these fatty acids to excessive oxidative stress
- This dysaerobic state leads to decreased growth of connective tissue and degeneration
- Increased membrane permeability
- Excess tissue alkalinity and excess systemic acidity
Too Many Fatty Acids, Not Enough Sterols
Dysaerobic Patterns
- Common Symptoms – diarrhea, burnt out fatigue, insomnia, anxiety oliguria, sharp pain (tissue alkalinity) responds well to prednisone
- Lab Findings – may have -high CRP, high serum cholesterol, low estrogen, low progesterone, low cortisol, increased symptoms during menses
- Metabolic Tests – high urine SG > 15, low urine pH < 6.1, high saliva pH > 6.7, rapid absorption of skin wheel
- Benefit from relatively high cholesterol foods
- Reacts poorly to sulfur products – dysaerobic symptoms
Dysaerobic Overview
- Dysaerobic (dysfunctional use of oxygen) = excess FA Deficient in sterols = chloride pulled into FA leaving behind carbonates that cause tissue alkalinity- Saliva alkaline Treatment – High Cholesterol Diet, Oxygenic D+(glycerol and butanol), Oxygenic D, Glycine
Therapeutic Agents Effects on Imbalances
